20 Eye Drops for Protein Build-Up Relief

Discover the best eye drops for protein build-up to refresh your vision swiftly. Clear, effective solutions for bright, revitalized eyes await you.
BrandMy RatingPrice
Rohto
Best Value Option
9.0/10
Biotrue
Best for Contact Lens Wearers
9.4/10
Blink
Best for Dry Eyes
9.2/10
Opti-Free
Best for Deposit Prevention
9.6/10
Blink
9.6/10

Best Eye Drops for Protein Build Up

Struggling with protein build-up in your eyes can be discomforting and distracting, but finding the right eye drops doesn't have to be a maze. Dive into our curated list of the best eye drops designed to swiftly soothe and clear away those pesky protein deposits, so your eyes stay fresh, bright, and ready for anything.

Best Value Option: Rohto

Rohto Maximum Strength Eye Drops, Redness Relief for Itchy Eye, Dry Eye Relief, and Irritated Eyes, Pack of 1
Highlights
Fast-acting relief
Redness reduction
Long-lasting soothing

As the Best Value Option, it offers maximum contact lens relief and effectively tackles dryness with a proven, fast-acting formula.

The Freshkick technology delivers an instant cooling sensation that instantly soothes irritated, red eyes, providing relief that lasts up to 8 hours.

While the initial cooling can be a bit intense and the price might seem steep for the size, the overall performance justifies the investment.

For quick, reliable relief from burning and dryness, this eye drop is a fantastic choice—especially if you're seeking great value and fast results.

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Price history for Rohto on Amazon

Best for Contact Lens Wearers: Biotrue

Biotrue Hydration Boost Eye Drops, Preservative Free, Soft Contact Lens Friendly for Irritated and Dry Eyes from Bausch + Lomb, Naturally Inspired, 0.33 FL OZ (10 mL)
Highlights
Preservative-free formula
Contact lens friendly
Instant moisture

Biotrue Hydration Boost Eye Drops are a game-changer for contact lens wearers, offering instant relief with a specially formulated blend of hyaluronan, antioxidants, and electrolytes.

The preservative-free design ensures your eyes stay moisturized without irritation, even under environmental stressors or screen fatigue.

Plus, they're completely compatible with soft contact lenses, allowing application while you're wearing them—no need to remove.

The small bottle might be a little tricky to handle, but the soothing hydration they deliver makes it worth it.

Overall, a fantastic choice for reliable, long-lasting eye comfort.

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Price history for Biotrue on Amazon

Best for Dry Eyes: Blink

Blink Tears Lubricating Eye Drops, 0.5 fl oz (15 mL) Eye Care for Mild to Moderate Dry Eyes, Hyaluronate for Boosting Hydration, Moisturizing & Soothing Eye Drops for Dry Eyes
Highlights
Immediate relief
Long-lasting hydration
Trusted brand

Blink Tears Lubricating Eye Drops is our top pick for dry eyes, thanks to its powerful hyaluronate formula that delivers instant relief and long-lasting hydration. The drops quickly rebuild your tear film, providing a soothing shield against dryness and discomfort.

Ideal for mild to moderate cases, they keep your eyes moist without the need for constant reapplication.

Plus, trust in the trusted brand makes these drops a reliable choice for ongoing eye comfort.

Keep in mind, though, they may need frequent doses and might not be best for severe dryness.

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Price history for Blink on Amazon

Best for Deposit Prevention: Opti-Free Puremoist

Opti-Free Puremoist Rewetting Drops, 12-mL
Highlights
Refreshes and moisturizes
Reduces irritation
Compatible with all contacts

Opti-Free Puremoist Rewetting Drops earn our top spot for Deposit Prevention because they effectively help remove particles that cause irritation, keeping your eyes comfortable and lenses clear.

The soothing moisture boost makes those long wear sessions more bearable, and the fact that it’s compatible with all silicone hydrogel and soft contact lenses is a huge plus.

While it’s primarily for contact lens wearers and might not prevent all deposits, this product is a reliable choice for maintaining healthy, irritation-free eyes in a quick, fuss-free manner.

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Price history for Opti-Free Puremoist on Amazon

Blink-N-Clean

Blink-N-Clean Lens Drops, Rewetting Drops for Contact Lenses, Instant Dry Lens Moisturizing, for Soft & RGP Lenses, 0.5 fl oz
Highlights
Instant moisture relief
Suitable for soft & RGP lenses
Compact & portable design

This eye drop keeps your lenses feeling fresh and your vision crystal clear in an instant.

It provides quick moisture to dry lenses, making those long days a lot more comfortable.

Plus, it’s gentle and easy to use, perfect for soft and RGP lenses alike.

Its compact size means slipping it into your bag is a breeze, so you can refresh on the go.

While the bottle is small and it might not tackle severe dryness, for light to moderate use, it’s a solid choice.

Overall, a reliable option for daily lens hydration and comfort.

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Price history for Blink-N-Clean on Amazon

Visine

Visine Dry Eye Relief Lubricant Eye Drops with Polyethylene Glycol 400 to Moisturize and Soothe Irritated, Gritty and Dry Eyes, Designed to Work Like Real Tears, 0.5 fl. oz
Highlights
Provides moisture relief
Portable and convenient
Soothes irritated eyes

Visine Dry Eye Relief Lubricant Drops offer instant soothing relief for dry, gritty eyes—perfect after long hours staring at screens or during those dry, allergy-prone days.

The drops mimic natural tears with a blend of ingredients including polyethylene glycol 400, providing a comfortable hydration that helps combat irritation and burning.

Plus, its compact bottle makes it super easy to carry around, so you can get relief anytime, anywhere.

While it may not work for every eye type and some may find it pricier than other options, it’s a reliable choice for quick, on-the-go moisture.

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Price history for Visine on Amazon

Bausch & Lomb Eye Drops for Protein Build Up

Bausch & Lomb Advanced Eye Relief Maximum Redness Reliver, 0.5 Fl Oz (Pack of 6)
Highlights
Trusted brand
Effective redness relief
Soothes dry eyes

Bausch + Lomb's Advanced Maximum Redness Reliever Eye Drops are a trusted choice for quick relief from eye redness and irritation.

Their effectiveness lies in their fast-acting formula, which quickly soothes dry, irritated eyes and visibly reduces redness.

The moisturizing properties help keep your eyes comfortable, especially during long periods of screen time or allergy season.

While they excel in relieving redness and dryness, they don't specifically target protein buildup—so this is more of a redness fix than a comprehensive solution.

Overall, a reliable, high-quality option for rapid eye relief.

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Price history for Bausch & Lomb on Amazon

Alaway

Alaway Antihistamine Eye Drops, Allergy Relief from Itchy Eyes, Works in Minutes, Provides Relief for up to 12 Hours, Clinically Tested Prescription Strength Formula, 0.34 Fl Oz
Highlights
Fast allergy relief
Clinically tested formula
Trusted brand for 150+ years

Bausch + Lomb’s Alaway delivers fast, clinically proven relief from itchy, allergy-ridden eyes—perfect for those quick fix moments.

Its prescription-strength formula targets allergy symptoms at the source, outperforming many allergy pills in speed.

The drops are easy to use, although the small bottle size might mean frequent refills.

While it does have a slight sting for some users, the benefits of rapid relief and trusted quality make it a solid choice.

If you’re after immediate comfort from eye allergies, Alaway is definitely worth a try.

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Price history for Alaway on Amazon

Biotrue

Biotrue Hydration Boost Eye Drops for Irritated, Dry Eyes in Single Dose Vials from Bausch + Lomb, Instant Moisture, Preservative Free, pH Balanced, Naturally Inspired, Pack of 30 Vials
Highlights
Instant moisture delivery
Preservative-free formula
Convenient single-dose vials

Biotrue Hydration Boost offers instant relief for dry, irritated eyes, especially after long hours on screens or outdoors in harsh environments.

The preservative-free formula is gentle and pH balanced, ensuring comfort with every drop.

Plus, the single-dose vials make application quick and mess-free—great for on-the-go refreshment.

While the cost might be a bit high for frequent use, the powerful hydration boost and trustworthiness of Bausch + Lomb make it worth considering for those seeking reliable eye relief.

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Price history for Biotrue on Amazon

Opcon-A Eye Drops for Protein Build Up

Opcon-A Allergy Eye Drops by Bausch + Lomb, for Itch and Redness Relief, Red and Itchy Eyes Antihistamine Eye Drop, Clinically Proven Treatment, 0.5 Fl Oz (Pack of 3)
Highlights
Quick allergy relief
Mild stinging sensation
Affordable price

Opcon A eye drops deliver quick relief from allergen-induced redness and itchiness, making them a go-to for those sudden eye flare-ups.

The clever combination of an antihistamine with a redness reliever tackles bothersome symptoms effectively, though it doesn’t last as long as some premium options.

We appreciate the mild stinging — a small price for fast comfort — and the affordable price point makes them accessible for daily use.

Keep in mind, they offer temporary relief and the product has been discontinued by the manufacturer, but for initial allergy attacks, they get the job done with a trusted brand behind them.

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Price history for Opcon-A on Amazon

TRP Natural Eyes

Natural Eyes Pink Eye Relief Fast Dissolving Tablets
Highlights
Natural active ingredients
Fast dissolving tablets
Relieves pink eye symptoms

Natural Eyes offers a gentle yet effective solution with 5 natural active ingredients that provide quick relief from pink eye symptoms like redness, burning, and crusting.

The ultra-convenient fast-dissolving tablets make application easy — just pop one under your tongue three times a day.

While it's not a cure for underlying issues, it’s perfect for temporary relief and pairs well with soothing eye drops.

Keep in mind, consistent use for several days is needed for optimal results.

Overall, a natural, mess-free option for managing pink eye discomfort.

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Price history for TRP Natural Eyes on Amazon

Biotrue

Biotrue Hydration Boost Rehydrating Contact Lens Eye Drops from Bausch + Lomb, Hydrating, Preservative Free, Naturally Inspired, 0.33 FL Oz (10 mL)
Highlights
Natural ingredients
Long-lasting hydration
Preservative-free

Biotrue Hydration Boost for Contacts harnesses naturally inspired ingredients like hyaluronan and antioxidants to keep your eyes feeling fresh and comfortable.

The preservative-free formula and pH balance ensure that your eyes won't feel irritated, even after hours of wear.

While the small bottle size is a bit inconvenient and the 8-hour moisture window might not last all day for everyone's needs, the long-lasting hydration and natural composition make it a reliable choice for those seeking gentle, effective rewetting drops.

Perfect for quick refreshes between activities!

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Price history for Biotrue on Amazon

Refresh Eye Drops for Protein Build Up

Refresh Relieva Lubricant Eye Drops, 0.33 Fl Oz Sterile, Packaging may Vary
Highlights
Effective for dry eyes
Relieves eye irritation
Doctor recommended

Refresh harnesses an innovative formula that effectively soothes dry, irritated eyes with its unique Hydrocell technology, which keeps your eye surface well-hydrated.

It’s a favorite among eye care professionals, earning the top spot in doctor recommendations.

While the small bottle might be a bit limiting for those who need frequent reapplication, its powerful relief and trusted reputation make it worth the investment.

Perfect for contact lens wearers and those seeking quick comfort, this drops truly deliver on their promise of lasting hydration and irritation prevention.

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Price history for Refresh on Amazon

Refresh

Refresh Tears PF Preservative-Free Artificial Tears Lubricant Eye Drops, 0.33 fl oz (10 mL)
Highlights
Fast acting relief
Preservative-free formula
Trusted brand

The original strength formula provides quick relief for mild, occasional dry eyes, making it ideal for those moments when you need a fast, soothing boost.

The preservative-free formulation is perfect for sensitive eyes, ensuring comfort without discomfort.

Although the small size means you'll need to keep a backup handy, the soft squeeze bottle with double lockout ensures sterility and easy dosing.

Trusted by many and backed by decades of expertise, it’s a solid choice for on-the-go relief—just be mindful that the effects are temporary and dispensing can sometimes be tricky.

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Price history for Refresh on Amazon

Refresh

Refresh Optive Advanced Lubricant Eye Drops, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 30 Count
Highlights
Preservative-free
Hydrates dry eyes
On-the-go single use

The preservative-free formula makes it ideal for sensitive eyes, offering triple-action relief that lubricates, hydrates, and helps prevent tears from evaporating.

The Hydrocell technology ensures your eyes stay moisturized longer, maintaining their surface health.

Plus, the single-use vials make it super convenient to carry around and keep hygiene top-notch.

While it might be on the pricier side and requires multiple applications to fully combat dryness or redness, it truly delivers soothing relief.

Perfect for those seeking a gentle, reliable option on the go!

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Price history for Refresh on Amazon

Opti-Free Eye Drops for Protein Build Up

Opti-Free Replenish Rewetting Drops,10-mL,0.33 Fl Oz
Highlights
Instant hydration and relief
Suitable for all contact lenses
Long-lasting moisture

Opti-Free Replenish Rewetting Drops deliver an instant burst of hydration that can turn dry, irritated eyes into a refreshing oasis.

They effectively remove particles that cause discomfort and help prevent deposit buildup—key issues for contact lens wearers.

Plus, they’re suitable for all silicone hydrogel and soft lenses, making them versatile and easy to incorporate into daily routines.

While they're not specifically targeting eye buildup, their long-lasting moisture and soothing relief make them a reliable choice for anyone seeking quick comfort and clarity.

Overall, a solid option for contact lens users!

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Price history for Opti-Free on Amazon

Archie's Remedies

Dry Eye Relief, Ultra Lubricating Eye Drops, Clean Formula and Preservative-Free Vials, Single-Use, for Irritation and Red Eyes, Natural Tears, 30 Count
Highlights
Instant relief from dryness
Long-lasting hydration
Preservative-free, hygienic

Archie's Ultra Lubricating Single-Use Eye Drops deliver an instant boost of moisture that quickly soothes irritated, dry eyes—ideal for those quick relief moments.

The preservative-free formula means no harsh additives, making it safe for all eye types, including contact lens wearers.

Plus, the long-lasting hydration keeps discomfort at bay throughout the day, whether you're working at your desk or on the move.

The single-use vials are super convenient, hygienic, and mess-free, ensuring each drop feels fresh and trustworthy.

Perfect for quick, natural comfort!

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Price history for Archie's Remedies on Amazon

Visine

Visine Red Eye Hydrating Comfort Redness Relief and Lubricant Eye Drops to Help Moisturize and Relieve Red Eyes Due to Minor Eye Irritations Fast, Tetrahydrozoline HCl, 0.5 fl. oz
Highlights
Fast-acting redness relief
Provides moistening comfort
Portable and travel-friendly

Visine Red Eye Hydrating Comfort offers lightning-fast relief for irritated, red eyes—often in just 30 seconds!

The formula is designed to hydrate and soothe, making it perfect after long hours staring at screens or exposure to smoke.

Its compact size means you can toss it in your pocket or purse for on-the-go comfort wherever you need it.

While overuse can lead to dryness or rebound redness, used sparingly, it really helps keep your eyes comfortable and refreshed during busy days.

A solid choice for quick, temporary relief!

Be sure to also check out the best gluten free protein bars for more options! Also, here is the price history so you know exactly when to buy!

Price history for Visine on Amazon

Systane Hydration Eye Drops for Protein Build Up

Systane Hydration Multi-Dose Preservative-Free Eye Drops Dry Eye Relief Twin Pack (2x10ml)
Highlights
Fast hydrating relief
Preservative free
Long-lasting comfort

Hydrates quickly and keeps your eyes comfortable for hours, making it ideal for those dealing with dry, tired eyes.

The preservative-free formula is gentle and safe, even for sensitive eyes, while the hyaluronate adds an extra layer of hydration to combat dryness.

Plus, it's safe to use with all contact lenses, which is a huge plus.

The only minor drawback is the bottle design—it's a bit messy and requires shaking before each use.

Overall, this eye drop is a trusted choice for quick, reliable relief that lasts.

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Price history for Systane Hydration on Amazon

Rohto Dry Aid

Rohto Dry Aid Lubricant Eye Drops, Fast Relief for Dry Eyes, Long-Lasting Hydration, Dry Eye Symptom Relief, Moisturizing and Soothing Eye Drops for Dry Eyes, Contact Lens-Friendly, 0.34 fl oz
Highlights
Quick, long-lasting relief
Soothes dry, irritated eyes
Trusted eye care brand

Rohto Dry Aid Lubricating Eye Drops deliver fast, long-lasting hydration that really silences dry, irritated eyes—sometimes for up to 12 hours!

The advanced Liquid Shield Technology mimics natural tears, ensuring your eyes stay comfortable and moisture-rich all day.

Plus, they’re safe for contact lens wearers and free from preservatives, making them a reliable choice.

The cooling and hydrating sensation provides immediate relief, though some users might experience a slight tingling.

Overall, Rohto's trusted reputation and proven effectiveness make these drops a top pick for quick, sustained comfort.

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Price history for Rohto Dry Aid on Amazon

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